Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation
- Creator: Salvato, Ilaria , Ricciardi, Luca , Vatrella, Alessandro , Nucera, Francesco , Brun, Paola , Caicci, Federico , Dama, Paola , Stiff, Thomas , Castellano, Leandro , Idrees, Sobia , Johansen, Matt D. , Faiz, Alen , Dal Col, Jessica , Wark, Peter A. , Hansbro, PM , Adcock, IM , Caramori, G , Stellato, C , Nigro, Annunziata , Giurato, Giorgio , Memoli, Domenico , Sellitto, Assunta , Lamparelli, Erwin Pavel , Crescenzi, Maria Assunta , Vitale, Monica
- Resource Type: journal article
- Date: 2023
IL-33 Expression Is Lower in Current Smokers at Both Transcriptomic and Protein Level
- Creator: Faiz, Alen , Mahbub, Rashad M. , Heijink, Irene H. , Massip, Florian , de Biase, Maria Stella , Schwarz, Roland F. , Adcock, Ian M. , Chung, Kian F. , van der Does, Anne , Hiemstra, Pieter S. , Goulaouic, Helene , Xing, Heming , Boedijono, Fia Sabrina , Wark, Peter A. , ., , Tomassen, Milan I. , Kooistra, Wierd , Timens, Wim , Nawijn, Martijn , Hansbro, Philip M. , Johansen, Matt D. , Pouwels, Simon D.
- Resource Type: journal article
- Date: 2023
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase
- Creator: Liu, Gang , Haw, Tatt Jhong , Hortle, Elinor , Pickles, Sophie , Rojas-Quintero, Joselyn , Estepar, Raul San Jose , Marshall, Jacqueline E. , Kim, Richard Y. , Collison, Adam M. , Mattes, Joerg , Idrees, Sobia , Faiz, Alen , Starkey, Malcolm R. , Hansbro, Nicole G. , Fukui, R , Murakami, Y , Cheng, HS , Tan, NS , Chotirmall, SH , Horvat, Jay C. , Foster, Paul S. , Oliver, BG , Polverino, F , Philp, Ashleigh M. , Ieni, A , Monaco, F , Caramori, G , Sohal, SS , Bracke, KR , Wark, Peter A. , Adcock, IM , Miyake, K , Sin, DD , Hansbro, Philip M. , Pavlidis, Stelios , Nalkurthi, Christina , Nair, Prema M. , Gomez, Henry M. , Hanish, Irwan , Hsu, Alan CY
- Resource Type: journal article
- Date: 2023
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Adverse roles of mast cell chymase-1 in COPD
- Creator: Liu, Gang , Jarnicki, Andrew G. , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Paudel, Keshav R. , Sohal, Sukhwinder S. , Wark, Peter A. , Oliver, Brian G. , Hansbro, Philip M. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica
- Resource Type: journal article
- Date: 2022
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
- Creator: Johansen, Matt D. , Mahbub, Rashad M. , Gallego-Ortega, David , Britton, Warwick J. , Saunders, Bernadette M. , Wark, Peter A. , Faiz, Alen , Hansbro, Philip M. , Idrees, Sobia , Nguyen, Duc H. , Miemczyk, Stefan , Pathinayake, Prabuddeha , Nichol, Kristy , Hansbro, Nicole G. , Gearing, Linden J. , Hertzog, Paul J.
- Resource Type: journal article
- Date: 2022
Factors associated with nonadherence to inhaled corticosteroids for asthma during pregnancy
- Creator: Robijn, Annelies L. , Barker, Daniel , Gibson, Peter G. , Giles, Warwick B. , Clifton, Vicki L. , Mattes, Joerg , Peek, Michael J. , Barrett, Helen L. , Seeho, Sean K. , Callaway, Leonie K. , Abbott, Alistair , Attia, John , Wark, Peter A. , Jensen, Megan E. , Murphy, Vanessa E.
- Resource Type: journal article
- Date: 2021
Hemopexin: a novel anti-inflammatory marker for distinguishing COPD from asthma
- Creator: Winter, Natasha A. , Gibson, Peter G. , Fricker, Michael , Simpson, Jodie L. , Wark, Peter A. , McDonald, Vaness M.
- Resource Type: journal article
- Date: 2021
microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis
- Creator: Kim, Richard Y. , Sunkara, Krishna P. , Ricciardolo, Fabio L. M. , Di Stefano, Antonino , Haw, Tatt Jhong , Liu, Gang , Ferguson, Angela L. , Palendira, Umamainthan , Wark, Peter A. , Conickx, Griet , Mestdagh, Pieter , Brusselle, Guy G. , Bracke, Ken R. , Caramori, Gaetano , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Jarnicki, Andrew G. , Donovan, Chantal , Hsu, Alan C. , Ieni, Antonio , Beckett, Emma L. , Galvão, Izabela , Wijnant, Sara
- Resource Type: journal article
- Date: 2021
Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease
- Creator: Lu, Zhe , Van Eeckhoutte, Hannelore P. , Vanden Berghe, Tom , Brusselle, Guy G. , Horvat, Jay C. , Murphy, James M. , Wark, Peter A. , Bracke, Ken R. , Fricker, Michael , Hansbro, Philip M. , Liu, Gang , Nair, Prema M. , Jones, Bernadette , Gillis, Caitlin M. , Nalkurthi, B. Christina , Verhamme, Fien , Buyle-Huybrecht, Tamariche , Vandenabeele, Peter
- Resource Type: journal article
- Date: 2021
The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders
- Creator: Chong, Wai Chin , Shastri, Madhur D. , Peterson, Gregory M. , Patel, Rahul P. , Pathinayake, Prabuddha S. , Dua, Kamal , Hansbro, Nicole G. , Hsu, Alan C. , Wark, Peter A. , Shukla, Shakti Dhar , Johansen, Matt D. , Schroder, Kate , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2021
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
- Creator: Bowerman, Kate L. , Rehman, Saima Firdous , Yang, Ian A. , Wark, Peter A. , Hugenholtz, Philip , Hansbro, Philip M. , Vaughan, Annalicia , Lachner, Nancy , Budden, Kurtis F. , Kim, Richard Y. , Wood, David L. A. , Gellatly, Shaan L. , Shukla, Shakti D. , Wood, Lisa G.
- Resource Type: journal article
- Date: 2020
Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma
- Creator: Sánchez-Ovando, Stephany , Baines, Katherine J. , Barker, Daniel , Wark, Peter A. , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2020
Enhancing tristetraprolin activity reduces the severity of cigarette smoke-induced experimental chronic obstructive pulmonary disease
- Creator: Nair, Prema M. , Starkey, Malcolm R. , Haw, Tatt Jhong , Liu, Gang , Collison, Adam M. , Mattes, Joerg , Wark, Peter A. , Morris, Jonathan C. , Verrills, Nikki M. , Clark, Andrew R. , Ammit, Alaina J. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2019
Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis
- Creator: Liu, Gang , Cooley, Marion A. , Jones, Berrnadette , Hansbro, Nicole G. , Wark, Peter A. , Horvat, Jay C. , Argraves, W. Scott , Oliver, Brian G. , Knight, Darryl A. , Burgess, Janette K. , Hansbro, Philip M. , Jarnicki, Andrew G. , Borghuis, Theo , Nair, Prema M. , Tjin, Gavin , Hsu, Alan C. , Haw, Tatt Jhong , Fricker, Michael , Harrison, Celeste L.
- Resource Type: journal article
- Date: 2019
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
- Creator: Starkey, Malcolm R. , Plank, Maximilian W. , Donovan, Chantal , Hansbro, Nicole G. , Nguyen, Duc H. , Nair, Prema Mono , Kim, Richard Y. , Horvat, Jay C. , Kaiko, Gerard E. , Durum, Scott K. , Wark, Peter A. , Sin, Don D. , Casolari, Paolo , Caramori, Gaetano , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Papi, Alberto , Pavlidis, Stelios , Guo, Yike , Cameron, Guy J. M. , Haw, Tatt Jhong , Tam, Anthony , Obiedat, Maen
- Resource Type: journal article
- Date: 2019
RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses
- Creator: Hayman, Thomas J. , Hsu, Alan C. , Wark, Peter A. , Kedzierska, Katherine , Masters, Seth L. , Belz, Gabrielle T. , Binder, Marco , Hansbro, Philip M. , Nicola, Nicos A. , Nicholson, Sandra E. , Kolesnik, Tatiana B. , Dagley, Laura F. , Willemsen, Joschka , Tate, Michelle D. , Baker, Paul J. , Kershaw, Nadia J. , Kedzierski, Lukasz , Webb, Andrew I.
- Resource Type: journal article
- Date: 2019
Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease
- Creator: Donovan, Chantal , Starkey, Malcolm R. , Horvat, Jay C. , Wark, Peter A. , Foster, Paul S. , McKenzie, Andrew N. J. , Hansbro, Philip M. , Kim, Richard Y. , Rana, Batika M. J. , Barlow, Jillian L. , Jones, Bernadette , Haw, Tatt Jhong , Mono Nair, Prema , Budden, Kurtis , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2019
Trends in asthma self-management skills and inhaled corticosteroid use during pregnancy and postpartum from 2004 to 2017
- Creator: Robijn, Annelies L. , Jensen, Megan E. , Gibson, Peter G. , Powell, Heather , Giles, Warwick B. , Clifton, Vicki L. , Mattes, Joerg , Peek, Michael J. , Barrett, Helen L. , Seeho, Sean K. , Callaway, Leonie K. , Abbott, Alistair , Attia, John , Wark, Peter A. , Murphy, Vanessa E.
- Resource Type: journal article
- Date: 2019